The term “leaky gut” has gained a lot of attention in recent years.
Also known as increased intestinal permeability, it’s a condition in which gaps in your intestinal walls start to loosen. This allows larger substances, such as bacteria, toxins and undigested food particles, to pass across the intestinal walls into your bloodstream.
Studies have shown that increased intestinal permeability may be connected to several chronic and autoimmune diseases like type 1 diabetes and celiac disease.
This article takes a look at leaky gut syndrome and its causes. It also includes a list of foods that aid digestive health and a sample meal plan for one week.
Leaky gut syndrome is a condition that affects your digestive system.
The digestive system consists of many organs that collectively break down food, absorb nutrients and water and remove waste products. It also acts as a barrier between your gut and bloodstream to prevent harmful substances from entering your body (1, 2).
Most nutrient and water absorption occurs in your intestines. Your intestines have tight junctions, or small gaps, that allow nutrients and water to pass into your bloodstream.
How easily substances pass across the intestinal walls is known as intestinal permeability.
In leaky gut syndrome, these tight junctions loosen, potentially allowing harmful substances like bacteria, toxins and undigested food particles to enter your bloodstream.
This is thought to trigger widespread inflammation and stimulate an immune reaction (3).
Yet, there is little evidence to prove that leaky gut syndrome is a serious problem. As a result, it’s not recognized as a medical diagnosis by mainstream physicians.
On the other hand, many alternative practitioners believe leaky gut syndrome is linked to various conditions, including autoimmune diseases, migraines, autism, food sensitivities, skin conditions, brain fog and chronic fatigue.
Increased intestinal permeability exists and occurs alongside many diseases. However, it’s not clear if it’s a symptom or underlying cause of chronic disease (4).
Summary Leaky gut syndrome, or increased intestinal permeability, occurs when the tight junctions of your intestinal walls loosen. This may allow harmful substances, such as bacteria, toxins and undigested food particles, to pass into your bloodstream.
The exact cause of leaky gut syndrome is a mystery.
However, increased intestinal permeability is well known and occurs alongside several chronic diseases, including celiac disease and type 1 diabetes (5).
Zonulin is a protein that regulates tight junctions. Research has shown that higher levels of this protein may loosen tight junctions and increase intestinal permeability (6, 7).
Two factors may stimulate higher zonulin levels — bacteria and gluten (8).
There is consistent evidence that gluten increases intestinal permeability in people with celiac disease (9, 10).
However, research in healthy adults and those with non-celiac gluten sensitivity shows mixed results. While test-tube studies have found that gluten can increase intestinal permeability, human-based studies have not had the same effect (10, 11, 12).
Aside from zonulin, other factors can also increase intestinal permeability.
Research shows that higher levels of inflammatory mediators, such as tumor necrosis factor (TNF) and interleukin 13 (IL-13), or the long-term use of non-steroidal anti-inflammatory drugs (NSAIDS), such as aspirin and ibuprofen, may increase intestinal permeability (13, 14, 15, 16).
Furthermore, low levels of healthy gut bacteria may have the same effect. This is called gut dysbiosis (17).
Summary The exact cause of leaky gut syndrome remains a mystery, but certain proteins like zonulin and markers of inflammation provide some clues. Other potential causes include long-term NSAID use and an imbalance of gut bacteria known as gut dysbiosis.
As leaky gut syndrome isn’t an official medical diagnosis, there is no recommended treatment.
Yet, you can do plenty of things to improve your digestive health.
One is to eat a diet rich in foods that aid the growth of beneficial gut bacteria. An unhealthy collection of gut bacteria has been linked to poor health outcomes, including chronic inflammation, cancers, heart disease and type 2 diabetes (18).
The following foods are great options for improving your digestive health:
Summary A diet that promotes digestive health should focus on fibrous vegetables, fruits, fermented vegetables, cultured dairy products, healthy fats and lean, unprocessed meats.
Avoiding certain foods is equally important for improving your gut health.
Some foods have been shown to cause inflammation in your body, which may promote the growth of unhealthy gut bacteria linked to many chronic diseases (19).
The following list contains foods that may harm healthy gut bacteria, as well as some that are believed to trigger digestive symptoms, such as bloating, constipation and diarrhea:
Summary Avoiding processed junk foods, alcohol, sugary beverages, refined oils and artificial sweeteners may aid the growth of healthy gut bacteria. Cutting out foods containing gluten or common stimulants of digestive symptoms may also help.
Below is a healthy one-week sample menu for improving your digestive health.
It focuses on incorporating foods that promote the growth of healthy gut bacteria while removing foods that are notorious for causing uncomfortable digestive symptoms.
Some menu items contain sauerkraut, which is a type of fermented cabbage that is easy, simple and inexpensive to prepare. You can learn how to make sauerkraut here.
Summary A healthy gut menu should be rich in fruits, vegetables and lean protein. Fermented vegetables like sauerkraut or cultured dairy products like Greek yogurt are also excellent additions, as they’re a great source of healthy gut bacteria.
Although diet is key to improving gut health, there are plenty of other steps you can take.
Here are some more ways to improve your gut health:
If you think you have leaky gut syndrome, consider getting tested for celiac disease.
The two disorders can have overlapping symptoms.
Some people also find that diets like the Gut and Psychology Syndrome (GAPS) diet may ease leaky gut symptoms. However, this particular diet is incredibly restrictive and has no scientific studies to support its health claims.
Summary Aside from diet, try taking a probiotic supplement, reducing your stress levels, sleeping more, avoiding smoking and limiting alcohol intake to improve your gut health.
Leaky gut syndrome is also known as increased intestinal permeability.
It’s a condition in which gaps in the intestinal walls may widen, allowing bacteria, toxins and undigested food particles to pass through the intestinal walls into your bloodstream.
However, leaky gut syndrome is not a diagnosis recognized by mainstream physicians, as there is little evidence to prove that it’s a serious health problem.
Increased intestinal permeability occurs alongside chronic diseases like celiac disease and type 1 diabetes. However, it may be a symptom of these diseases, rather than a cause.
That said, there are plenty of steps you can take to improve your digestive health.
To combat leaky gut syndrome, eat foods that promote the growth of healthy gut bacteria, including fruits, cultured dairy products, healthy fats, lean meats and fibrous and fermented vegetables.
Avoid processed and refined junk foods.
You can also take probiotic supplements, reduce stress, limit NSAID use, avoid alcohol and get more sleep.